Vivitonin datasheet

Below is the product datasheet. This has been provided by the manufacturer and should always be provided with the medication. For a non-technical article, please click the link in the blue bar above.
 
 

Introduction

Company name: Intervet / Schering-Plough Animal Health
Address: Walton Manor
Walton
Milton Keynes
MK7 7AJ
Telephone: 01908 685685 (Customer Support Centre)
Telephone: 0370 060 3380 (Switchboard)
Fax: 01908 685555
Email: support.uk@intervet.com
Website: www.intervet.co.uk

Presentation

Vivitonin 50 mg tablets are orange-yellow, film-coated tablets, quarter-scored on one side. Each tablet contains 50 mg of the xanthine derivative Propentofylline.
Vivitonin 100 mg tablets are orange-yellow, oblong film-coated tablets, half-scored on one side. Each tablet contains 100 mg of the xanthine derivative Propentofylline.

Uses

For improvement in dullness, lethargy and overall demeanour in dogs. Vivitonin is particularly useful in older dogs, where it may increase willingness to exercise and exercise tolerance.
Propentofylline has been shown to increase blood flow, particularly of the heart and skeletal muscle. It also increases the blood flow of the brain and therefore its oxygen supply, without increasing the brain's glucose demand.
It has a modest positive chronotropic effect and a marked positive inotropic effect. In addition, it has been shown to have an anti-arrhythmic effect in dogs with myocardial ischemia and a bronchodilator action equivalent to that of aminophylline.
Propentofylline inhibits platelet aggregation and improves the flow properties of erythrocytes. It has a direct effect on the heart and reduces peripheral vascular resistance thereby lowering cardiac load.
Some symptoms or conditions related to impaired blood circulation where Vivitonin may be of benefit are:
•Dullness, lethargy and depressed demeanour.
•Decreased willingness to exercise and exercise tolerance.
•Arryhthmia due to myocardial ischaemia.
•Conditions requiring improved circulation in the heart, brain and skeletal muscle.

Dosage and administration

Vivitonin 50 mg tablets
One tablet per 10 kg bodyweight twice a day. The tablets may be halved.
Dogs of less than 5 kg may receive a quarter tablet twice a day.
Divide the tablets in halves and quarters with a knife or with a tablet splitter.
Dogs of 20 kg or more can be given Vivitonin 100 mg tablets.
Vivitonin 100 mg tablets
One tablet per 20 kg bodyweight twice a day.
Vivitonin 100 mg tablets may be halved but should not be quartered.
For larger dogs more accurate dosing may be achieved using a combination of Vivitonin 100 mg and Vivitonin 50 mg tablets. Divide the tablets in halves with a knife or with a tablet splitter.
Dogs of less than 20 kg can be given Vivitonin 50 mg tablets.

Weight	50mg	100mg
< 5 kg	¼ tab bid	-
5 kg	½ tab bid	-
10 kg	1 tab bid	-
15 kg	1½ tabs bid	-
20 kg	-	1 tab bid
30 kg	-	1½ tabs bid
40 kg	-	2 tabs bid

 
The tablets can be administered directly onto the back of the dog's tongue or can be mixed in a small ball of food and should be administered at least 30 minutes before feeding.

Contra-indications, warnings, etc

Do not administer to pregnant bitches or breeding animals, as it has not yet been evaluated in this class of animal.
Specific diseases (e.g. kidney disease) should receive appropriate treatment.
Consideration should be given to rationalising the medication of dogs already receiving treatment for congestive heart failure or bronchial disease.
In the rare event of allergic skin reactions, treatment with the product should be stopped.
Operator warnings
Care should be taken to avoid accidental ingestion.
Wash hands after use.
For animal treatment only. Keep out of the reach and sight of children.

Pharmaceutical precautions

Do not store above 25°C. Store in a dry place.
Keep blister pack in outer carton.
Disposal
Dispose of empty packaging in the household refuse. Unused product should be returned to the veterinary surgeon for disposal.

Legal category

POM-V

Packaging Quantities

Vivitonin 50 mg tablets – Packs of 2 x 30 tablets.
Vivitonin 100 mg tablets – Packs of 6 x 10 tablets.

Further information

Nil.

Marketing authorisation number(s)

Vivitonin 50 mg tablets	Vm 01708/4417
Vivitonin 100 mg tablets	Vm 01708/4446